Blar i forfatter "Goeres, Darla M."

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    • Paired methods to measure biofilm killing and removal: a case study with Penicillin G treatment of Staphylococcus aureus biofilm 

      Ausbacher, Dominik; Lorenz, Lindsey A.; Pitts, Betsey; Stewart, Philip S.; Goeres, Darla M. (Journal article; Tidsskriftartikkel; Peer reviewed, 2017-12-30)
      Biofilms are microbial aggregates that show high tolerance to antibiotic treatments <i>in vitro</i> and <i>in vivo</i>. Killing and removal are both important in biofilm control, therefore methods that measure these two mechanisms were evaluated in a parallel experimental design. Kill was measured using the single tube method (ASTM method E2871) and removal was determined by video microscopy and ...

    • α,α-disubstituted β-amino amides eliminate Staphylococcus aureus biofilms by membrane disruption and biomass removal 

      Ausbacher, Dominik; Miller, Lindsey A.; Goeres, Darla M.; Stewart, Philip S.; Strøm, Morten Bøhmer; Fallarero, Adyary (Journal article; Tidsskriftartikkel; Peer reviewed, 2023-08-25)
      Bacterial biofilms account for up to 80% of all infections and complicate successful therapies due to their intrinsic tolerance to antibiotics. Biofilms also cause serious problems in the industrial sectors, for instance due to the deterioration of metals or microbial contamination of products. Efforts are put in finding novel strategies in both avoiding and fighting biofilms. Biofilm control is ...